구강작열감증후군과 우울장애의 양방향 연관성 분석
Bidirectional Association between Burning Mouth Syndrome and Depression Disorders
조혜민, 최혜미, 조남표,
소속 상세정보
조혜민 ( Cho Hye-Min ) - Seoul National University Hospital Biomedical Research Institute Laboratory of Emergency Medical Services
최혜미 ( Choi Hye-Mi ) - Chonbuk National University Department of Statistics
조남표 ( Cho Nam-Pyo ) - Chonbuk National University School of Dentistry Department of Oral Pathology
Abstract
The purpose of this study was to determine the bidirectional association between burning mouth syndrome (BMS) and depression disorders. Methods: A total of 854 pairs of BMS and 58 999 pairs of depression disorders matched 1:1 for age and sex were analyzed using conditional logistic regression models, which were adjusted for potential confounding factors. Results: Bidirectional analysis found that BMS was associated with depression disorders (odds ratio=4.64, P < 0.001) and depression disorders was also significantly associated with BMS (odds ratio=2.97, P < 0.001). Conclusion: These findings indicate a significant bidirectional association between BMS and depression disorders. The odds ratios suggest that BMS is a stronger predictor for incidence of depression disorders than depression disorders predicting incidence of BMS. Given this retrospective cohort design, the mechanisms underlying the association between BMS and depression disorders are not directly analyzed. Therefore, further investigation are needed to analyze the causality between BMS and depression disorders.
키워드
BMS; Depression disorders; Bidirectional association; Conditional logistic regression analysis
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